Watch & wait - Post neoadjuvant imaging for rectal cancer

Rectal cancer management has evolved over the past decade with the emergence of total neoadjuvant therapy (TNT). For select patients who achieve a clinical complete response following TNT, organ preservation by means of the watch-and-wait (WW) strategy is an increasingly adopted alternative that preserves rectal function and quality of life without compromising oncologic outcomes. Recently, published 5-year results from the OPRA trial demonstrated that organ preservation can be achieved in approximately half of patients managed with the WW strategy, with most local regrowth events occurring within two years.

Source: Clinical Imaging - April 19, 2024 Category: Radiology Authors: Maria El Homsi, Aron Bercz, Stephanie Chahwan, Maria Clara Fernandes, Sidra Javed-Tayyab, Jennifer S. Golia Pernicka, Josip Nincevic, Viktoriya Paroder, Lisa Ruby, J. Joshua Smith, Iva Petkovska Tags: Body Imaging Source Type: research