​Genuine Carbene Versus Carbene-Like Reactivity

Angew Chem Int Ed Engl. 2024 Apr 17:e202401020. doi: 10.1002/anie.202401020. Online ahead of print.ABSTRACTSinglet carbenes are not always isolable and often even elude direct detection. When they escape observation, their formation can sometimes be evidenced by in-situ trapping experiments. However, is carbene-like reactivity genuine evidence of carbene formation? Herein, using the first example of a spectroscopically characterized cyclic (amino)(aryl)carbene (CAArC), we cast doubt on the most common carbene trapping reactions as sufficient proof of carbene formation.PMID:38632078 | DOI:10.1002/anie.202401020

Source: Angewandte Chemie - April 17, 2024 Category: Chemistry Authors: Jan Lorkowski Patrick Yorkgitis Melinda R Serrato Milan Gembicky Cezary Pietraszuk Guy Bertrand Rodolphe Jazzar Source Type: research