Luciferase- and HaloTag-based reporter assays to measure small-molecule-induced degradation pathway in living cells

Nature Protocols, Published online: 18 April 2024; doi:10.1038/s41596-024-00979-zNanoLuciferase- and HaloTag-based screening technologies are versatile tools suitable for the live-cell analysis of the entire small-molecule-induced degradation cascade to uncover the mode of action of proximity-inducing compounds such as PROTACs.

https://www.nature.com/articles/s41596-024-00979-z

Source: Nature Protocols - April 18, 2024 Category: Biomedical Science Authors: Martin P. Schwalm Krishna Saxena Susanne M üller Stefan Knapp Source Type: research

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