Similar Efficacy and Lower Cost Associated with Ceftazidime Compared to Tobramycin Coupled with Vancomycin in Antibiotic Spacers in the Treatment of Periprosthetic Joint Infection

Vancomycin and tobramycin have traditionally been used in antibiotic spacers. In 2020, our institution replaced tobramycin with ceftazidime. We hypothesized that the use of ceftazidime/vancomycin (CV) in antibiotic spacers would not lead to an increase in treatment failure compared to tobramycin/vancomycin (TV).

Source: The Journal of Arthroplasty - April 15, 2024 Category: Orthopaedics Authors: Daniel Lewis, Brenna E. Blackburn, Jane Archibeck, Michael J. Archibeck, Lucas A. Anderson, Jeremy M. Gililland, Laura K. Certain, Christopher Pelt Tags: Proceedings of the Knee Society 2023 Source Type: research