An Automated Strategy to Calculate Medication Regimen Complexity

AMIA Annu Symp Proc. 2024 Jan 11;2023:1077-1086. eCollection 2023.ABSTRACTUnderstanding medication regimen complexity is important to understand what patients may benefit from pharmacist interventions. Medication Regimen Complexity Index (MRCI), a 65-item tool to quantify the complexity by incorporating the count, dosage form, frequency, and additional administration instructions of prescription medicines, provides a more nuanced way of assessing complexity. The goal of this study was to construct and validate a computational strategy to automate the calculation of MRCI. The performance of our strategy was evaluated by comparing our calculated MRCI values with gold-standard values, using correlation coefficients and population distributions. The results revealed satisfactory performance to calculate the sub-score of MRCI that includes dosage form and frequency (76 to 80% match with gold standard), and fair performance for sub-score related to additional direction (52% match with gold standard). Our automated strategy shows potential to help reduce the effort for manually calculating MRCI and highlights areas for future development efforts.PMID:38222413 | PMC:PMC10785893

Source: AMIA Annual Symposium Proceedings - January 15, 2024 Category: Bioinformatics Authors: Yuzhi Lu Ariel R Green Rosalphie Quiles Casey Overby Taylor Source Type: research