NHC-Catalyzed Enantioselective Transformations Involving α-Bromoenals

Chem Rec. 2024 Apr 8:e202400005. doi: 10.1002/tcr.202400005. Online ahead of print.ABSTRACTα-Haloenals, especially, α-bromoenals considered as one of the important building blocks in organic synthesis. They can participate in various (3+2)-, (3+3)-, (3+4)-, and (2+4)-annulation reactions with other organic molecules in the presence of an NHC catalyst to produce enantioenriched carbo-, and heterocyclic compounds. Herein, we have described NHC-catalyzed enantioselective transformations of α-bromoenals in the synthesis of various heterocycles, and carbocycles, as well as acyclic organic compounds.PMID:38587150 | DOI:10.1002/tcr.202400005

Source: Chemical Record - April 8, 2024 Category: Chemistry Authors: Fatemeh Doraghi Mahmoud Ameli Shirin Ansariashlaghi Bagher Larijani Mohammad Mahdavi Source Type: research