Ambient Temperature Metal-Free Thiomethylation of Chloroheteroarenes and Chloropurines

Chem Asian J. 2024 Apr 10:e202400114. doi: 10.1002/asia.202400114. Online ahead of print.ABSTRACTHerein, we report an in-situ mild and metal-free protocol for thiomethylation of heteroarenes in high yields. The thiomethylation of various chloropurines, nucleosides, and chloroheteroarenes has been accomplished offering easy access to agrochemicals and synthetic molecules useful for drug discovery.PMID:38598666 | DOI:10.1002/asia.202400114

Source: Chemistry, an Asian Journal - April 10, 2024 Category: Chemistry Authors: Manisha Patel Ra K Vora Yogesh S Sanghvi Anant Kapdi Source Type: research