Norepinephrine or just more epinephrine: which is the best vasopressor for post-arrest shock?

Shock is common after cardiac arrest, affecting up to two-thirds of patients.1,2 The pathophysiology of post-arrest shock is complex. Approximately half of out-of-hospital cardiac arrest (OHCA) patients have post-resuscitation myocardial dysfunction, and distributive shock is common due to systemic inflammation and reperfusion injury.2 –5 Vasopressors, the mainstay of treatment for post-arrest shock, are one of the most common interventions delivered to patients cardiac arrest, but the optimal agent remains unknown.

Source: Resuscitation - April 10, 2024 Category: Emergency Medicine Authors: Nicholas J. Johnson, Ari Moskowitz Tags: Editorial Source Type: research