Innovative, combinatorial and high-throughput approaches to degrader synthesis

Chem. Soc. Rev., 2024, Advance Article DOI: 10.1039/D3CS01127E, Tutorial ReviewRebecca Stevens, James D. F. Thompson, Julie C. L. Fournier, Glenn A. Burley, David J. Battersby, Afjal H. Miah In this review we highlight how the synthesis of degraders has evolved in recent years, in particular the application of high-throughput chemistry and screening approaches such as D2B and DEL technologies to expedite discovery timelines. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Chemical Society Reviews - April 10, 2024 Category: Chemistry Authors: Rebecca Stevens Source Type: research