Iodosulfonylation of [1.1.1]Propellane

Synthesis DOI: 10.1055/a-2290-6540 An efficient disubstituted functionalization of [1.1.1]propellane has been developed. The protocol utilizes sulfonyl hydrazides and N-iodosuccinimide, enabling the introduction of iodine and sulfonyl groups into bicyclo[1.1.1]pentane (BCP) in moderate to excellent yields. It has the advantages of simple operation, mild conditions, and broad substrate scope. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Synthesis - April 8, 2024 Category: Chemistry Authors: Chen, Mengke Ling, Min Huang, Zhiwei Cheng, Dongping Li, Jing-Hua Tags: paper Source Type: research