Nucleic acid-based drugs for patients with solid tumours

Nature Reviews Clinical Oncology, Published online: 08 April 2024; doi:10.1038/s41571-024-00883-1Nucleic acid-based therapies offer an alternative to traditional cancer treatment modalities, with promising data beginning to emerge. In this Review, the authors describe the design and development of nucleic acid-based therapies administered virally and non-virally, including discussions of the advantages and disadvantage of each approach, as well as the role of patient-specific factors such as the tumour microenvironment, and consider the most promising future research directions.
Source: Nature Reviews Clinical Oncology - Category: Cancer & Oncology Authors: Source Type: research