Mitochondrial dysfunction in type 2 diabetes: A neglected path to skeletal muscle atrophy

World J Orthop. 2024 Feb 18;15(2):101-104. doi: 10.5312/wjo.v15.i2.101. eCollection 2024 Feb 18.ABSTRACTOver the course of several decades, robust research has firmly established the significance of mitochondrial pathology as a central contributor to the onset of skeletal muscle atrophy in individuals with diabetes. However, the specific intricacies governing this process remain elusive. Extensive evidence highlights that individuals with diabetes regularly confront the severe consequences of skeletal muscle degradation. Deciphering the sophisticated mechanisms at the core of this pathology requires a thorough and meticulous exploration into the nuanced factors intricately associated with mitochondrial dysfunction.PMID:38464360 | PMC:PMC10921183 | DOI:10.5312/wjo.v15.i2.101
Source: World Journal of Orthopaedics - Category: Orthopaedics Authors: Source Type: research