Microbial synthesis of health-promoting inositols

Curr Opin Biotechnol. 2024 Mar 22;87:103114. doi: 10.1016/j.copbio.2024.103114. Online ahead of print.ABSTRACTD-chiro-inositol and scyllo-inositol are known for their health-promoting properties and promising as ingredients for functional foods. Strains of Bacillus subtilis and Corynebacterium glutamicum were created by metabolic engineering capable of inexpensive production of these two rare inositols from myo-inositol, which is the most common inositol in nature. In addition, further modifications have enabled the synthesis of the two rare inositols from the much-cheaper carbon sources, glucose or sucrose.PMID:38520822 | DOI:10.1016/j.copbio.2024.103114

Source: Current Opinion in Biotechnology - March 23, 2024 Category: Biotechnology Authors: Ken-Ichi Yoshida Michael Bott Source Type: research