Reduced Glucocorticoid Responsivity May Represent a Predisposing Marker That Leads to Additional Stress Vulnerability Traits

The phenomenon of posttraumatic stress disorder (PTSD) has puzzled clinicians and researchers for decades. Why is it that, following exposure to an apparently similar stressful event, a subset of individuals develops PTSD while others do not? What differentiates this subset of vulnerable individuals from the majority that exhibit a more resilient response profile? The answers to these questions may have substantial clinical potential, as they could enable the identification of biomarkers of stress vulnerability at close proximity or even prior to trauma exposure.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Commentary Source Type: research