Modeling Wound Chronicity In Vivo: The Translational Challenge to Capture the Complexity of Chronic Wounds
In an aging society with common lifestyle-associated health issues such as obesity and diabetes, chronic wounds pose a frequent challenge that physicians face in everyday clinical practice. Therefore, nonhealing wounds have attracted much scientific attention. Several in vitro and in vivo models have been introduced to deepen our understanding of chronic wound pathogenesis and amplify therapeutic strategies. Understanding how wounds become chronic will provide insights to reverse or avoid chronicity.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Anna-Lisa Pignet, Marlies Schellnegger, Andrzej Hecker, Lars-Peter Kamolz, Petra Kotzbeck Tags: Review Source Type: research
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