A peripheral blood mononuclear cell-based in vitro model: A tool to explore indoleamine 2, 3-dioxygenase-1 (IDO1)

CONCLUSION: IDO1 inhibition did not change T lymphocyte proliferation. We present herein an in vitro experimental model suitable to measure IDO1 expression and activity in circulating myeloid cells.PMID:38367683 | DOI:10.1016/j.ejphar.2024.176420

Source: European Journal of Pharmacology - February 17, 2024 Category: Drugs & Pharmacology Authors: Milene Gon çalves Alessia Furgiuele Emanuela Rasini Massimiliano Legnaro Marco Ferrari Alessandra Luini Paulo Rodrigues-Santos Francisco Caramelo Franca Marino Frederico C Pereira Marco Cosentino Source Type: research