Anti-inflammatory and immunomodulatory properties of polysaccharides in mushrooms

Curr Opin Biotechnol. 2024 Feb 14;86:103076. doi: 10.1016/j.copbio.2024.103076. Online ahead of print.ABSTRACTMushrooms are distinguished as important food-containing polysaccharides possessing potent anti-inflammatory and immunomodulating properties. These compounds belong mostly to polysaccharides that are mostly β-D-glucans. Among them, β-1,3-glucan with β-1,6 side chains of glucose residues, has more important roles in their properties. In this review, we have introduced polysaccharides mainly from Lentinula edodes and Pleurotus citrinopileatus with anti-inflammatory and immunomodulating properties. In addition, the mechanisms of activation of their physiological properties and signal cascade are also reviewed.PMID:38364705 | DOI:10.1016/j.copbio.2024.103076
Source: Current Opinion in Biotechnology - Category: Biotechnology Authors: Source Type: research