Engineering megabase-sized genomic deletions with MACHETE (Molecular Alteration of Chromosomes with Engineered Tandem Elements)
Nature Protocols, Published online: 07 February 2024; doi:10.1038/s41596-024-00953-9The authors introduce MACHETE (molecular alteration of chromosomes with engineered tandem elements), a clustered regularly interspaced short palindromic repeats directed Cas9-based system for the efficient deletion of megabase-sized genomic regions.
Source: Nature Protocols - Category: Biomedical Science Authors: Francisco M. Barriga Scott W. Lowe Source Type: research
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