Relapsing Polychondritis with Tracheobronchial Involvement: A Detailed Description of Two Pediatric Cases and Review of the Literature
Klin Padiatr DOI: 10.1055/a-2230-1521Relapsing polychondritis (RP) is a rare immune-mediated disease that primarily
affects the cartilaginous structures of the ears, nose and airways. The clinical
spectrum ranges from mild to severe disease characterized by progressive
destruction of cartilage in the tracheobronchial tree leading to airway
obstruction and acute respiratory failure. Early diagnosis is crucial to prevent
irreversible airway damage and life-threatening complications. Due to its rarity
and variability of symptoms, the diagnosis of RP is often delayed particularly
in childhood. To address this and increase awareness of this rare disease, we
present a detailed case report of two adolescent females affected by RP. We aim
to describe the clinical findings, consequences of a delayed diagnosis and
provide a review of the current literature. [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text
Source: Klinische Padiatrie - Category: Pediatrics Authors: Winter, Greta L öffelmann, Tara Chaya, Shaakira Kaiser, Hannah Prenzler, Nils Kristian Warnecke, Athanasia Wetzke, Martin Derlin, Thorsten Renz, Diane Stueber, Thomas L änger, Florian Sch ütz, Katharina Schwerk, Nicolaus Tags: Review Source Type: research