Noninvasive Imaging Techniques for Monitoring Cellular Response to Treatment in Stable Vitiligo

Vitiligo, an immune-mediated melanocyte destruction disorder (Harris, 2018), is often treated with immunomodulators and phototherapy (Bae et  al, 2017). Surgical interventions can achieve 45%–47% success with>90% repigmentation (Ju et  al, 2021) in stable vitiligo, but responses are unpredictable (Rajaram et al, 2017). Quantifying vitiligo treatment response to grafting is challenging because of the limited sensitivity of the Vitiligo Area Scoring Index (Gan et al, 2017; Komen et al, 2015), which can only capture macroscopic changes after 6–12 months (Gao et al, 2022).

Source: Journal of Investigative Dermatology - November 10, 2023 Category: Dermatology Authors: Jessica Shiu, Griffin Lentsch, Christopher M. Polleys, Pezhman Mobasher, Marissa Ericson, Irene Georgakoudi, Anand K. Ganesan, Mihaela Balu Tags: Letters to the Editor Source Type: research