Will variants of uncertain significance still exist in 2030?

The authors propose that many, if not most, variants of uncertain significance (VUSs) in coding regions will be resolved by 2030 and outline a confluence of changes making this possible. They note that achieving this goal will depend on the choices made now and in the next few years.

Source: The American Journal of Human Genetics - December 11, 2023 Category: Genetics & Stem Cells Authors: Douglas M. Fowler, Heidi L. Rehm Tags: Perspective Source Type: research