The competitive landscape of the dsRNA world

Recognition of foreign and endogenous dsRNAs is complicated by the sequence-independent binding of dsRNA-binding proteins. Cottrell, Andrews, and Bass review the synthesis, processing, binding, and degradation of dsRNAs. They highlight the mechanisms that prevent dsRNA sensors from binding to endogenous dsRNAs and activating innate immunity pathways.

Source: Molecular Cell - December 19, 2023 Category: Cytology Authors: Kyle A. Cottrell, Ryan J. Andrews, Brenda L. Bass Tags: Review Source Type: research