UltraFast PhotoInduced double duplex DNA invasion into a 400-mer dsDNA target

CONCLUSION: Based on the new design of pDDI probe with 5-cyano uridine led to a drastic increase in the efficiency of pDDI in (400-mer) double-stranded DNA with only 1 s of photo-irradiation.PMID:38154604 | DOI:10.1016/j.bmcl.2023.129597

Source: Bioorganic and Medicinal Chemistry Letters - December 28, 2023 Category: Chemistry Authors: Siddhant Sethi Hailili Zumila Yasuha Watanabe Junling Mo Kenzo Fujimoto Source Type: research