Deleterious effects of plasma-derived cellular debris in a porcine model of hemorrhagic shock

Recent studies identify large quantities of inflammatory cellular debris within Fresh Frozen Plasma (FFP). As FFP is a mainstay of hemorrhagic shock resuscitation, we used a porcine model of hemorrhagic shock and ischemia/reperfusion to investigate the inflammatory potential of plasma-derived cellular debris administered during resuscitation.

Source: Injury - December 23, 2023 Category: Orthopaedics Authors: Colin T. Buckley, Yannleei L. Lee, A. Michele Schuler, Raymond J. Langley, Matthew E. Kutcher, Robert Barrington, Jonathon P. Audia, Jon D. Simmons Source Type: research