Solvent extraction following oxidation of astatine for the use of a 211Rn –211At generator

Abstract211At is a promising nuclide among various α-emitters for targetedα therapy. In order to expand its accessibility, we're creating a211Rn –211At generator. Using N-bromosuccinimide (NBS), we successfully back-extracted211At from dodecane into 90% aqueous ethanol. NBS oxidizes211At into easily extractable compounds with high oxidation numbers, as confirmed through thin-layer chromatography.
Source: Journal of Radioanalytical and Nuclear Chemistry - Category: Nuclear Medicine Source Type: research