Bayesian estimation in NONMEM

AbstractBayesian estimation is a powerful but underutilized tool for answering drug development questions. In this tutorial, the principles of Bayesian model development, assessment, and prior selection will be outlined. An example pharmacokinetic (PK) model will be used to demonstrate the implementation of Bayesian modeling using the nonlinear mixed-effects modeling software NONMEM.

Source: CPT: Pharmacometrics and Systems Pharmacology - December 9, 2023 Category: Drugs & Pharmacology Authors: Curtis K. Johnston, Timothy Waterhouse, Matthew Wiens, John Mondick, Jonathan French, William R. Gillespie Tags: TUTORIAL Source Type: research