Unlocking the EGFR-mediated epitranscriptome: A pathway to novel therapies

In this issue, Lv et  al.1 explore EGFR-driven epitranscriptomic reprogramming in glioblastoma, revealing the pivotal role of the EGFR-ALKBH5-GCLM axis in ferroptosis protection. Their findings offer mechanistic insight and therapeutic strategies involving novel combination targets to enhance tumor responses.

Source: Molecular Cell - December 7, 2023 Category: Cytology Authors: Jovanka Gencel-Augusto, Trever G. Bivona Tags: Preview Source Type: research