Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly

Keidel et  al. present a structural view of the interplay between the cytoplasmic RNA exosome and its cofactor, the Ski238 complex, revealing the connection between the helicase activity of Ski2 and the nuclease activity of Rrp44.

Source: Molecular Cell - October 24, 2023 Category: Cytology Authors: Achim Keidel, Alexander K ögel, Peter Reichelt, Eva Kowalinski, Ingmar B. Schäfer, Elena Conti Tags: Article Source Type: research