Droplet-based cell-laden microgels for high-throughput analysis

Trends Biotechnol. 2023 Nov 10:S0167-7799(23)00301-3. doi: 10.1016/j.tibtech.2023.10.010. Online ahead of print.ABSTRACTCell-laden droplet microfluidics has revolutionized bulk biochemical analysis by offering compartmentalized microreactors for individual cells, but downstream operations of regular aqueous droplets are limited. Hydrogel matrix can provide a rigid scaffold for long-term culture of eukaryotic and prokaryotic cells, and can support several manipulations, facilitating subsequent high-throughput analysis of cellular heterogeneity.PMID:37953082 | DOI:10.1016/j.tibtech.2023.10.010

Source: Trends in Biotechnology - November 12, 2023 Category: Biotechnology Authors: Xiang Li Danshan Zhao Yuetong Wang He Huang Source Type: research