Maternally inherited siRNAs initiate piRNA cluster formation

Luo et  al. elucidate the mechanism behind the genesis of piRNA clusters, highlighting the role of siRNAs originating from repetitive sequences as initiators in this process. This discovery reveals the unanticipated involvement of siRNAs and offers insights into the origin of piRNA clusters.

Source: Molecular Cell - October 23, 2023 Category: Cytology Authors: Yicheng Luo, Peng He, Nivedita Kanrar, Katalin Fejes Toth, Alexei A. Aravin Tags: Article Source Type: research