The cell-cycle choreography of H3 variants shapes the genome

While the canonical core histones comprise typical nucleosomes, histone variants provide unique features linked to a variety of chromatin and DNA transactions. Delaney, Weiss, and Almouzni review the importance of the dynamics of histone H3 variants and how mutations of these variants or perturbations in their dynamics can impact genome integrity and disease.

Source: Molecular Cell - September 20, 2023 Category: Cytology Authors: Kamila Delaney, Nicole Weiss, Genevi ève Almouzni Tags: Review Source Type: research