Individual participant data from digital sources informed and improved precision in the evaluation of predictive biomarkers in Bayesian network meta-analysis.

We aimed to develop a network meta-analytic model for the evaluation of treatment effectiveness within predictive biomarker subgroups, by combining evidence from individual participant data (IPD) from digital sources (in the absence of RCTs) and aggregate data (AD).

Source: Journal of Clinical Epidemiology - October 31, 2023 Category: Epidemiology Authors: Chinyereugo M. Umemneku-Chikere, Lorna Wheaton, Heather Poad, Devleena Ray, Ilse Cuevas Andrade, Sam Khan, Paul Tappenden, Keith R. Abrams, Rhiannon K. Owen, Sylwia Bujkiewicz Tags: Original Article Source Type: research