SOSS-INTAC: a new gatekeeper of genomic integrity at the interface of transcription and R-loops

A recent Nature paper by Xu et  al.1 describes an important link between RNA polymerase II promoter-proximal pausing and genome stability orchestrated by liquid droplet formation to reduce unwanted R-loop accumulation.

Source: Molecular Cell - October 19, 2023 Category: Cytology Authors: Natalia Gromak Tags: Spotlight Source Type: research