Crystal structure and supramolecular features of a bis-urea-functionalized pillar[5]arene

The crystal structure of a bis-urea derivative based on A1/A2-functionalized pillar[5]arene (DUP) that encapsulates dimethyl formamide (DMF) inside the macrocyclic cavity is reported. The crystal structure of DUP · DMF, C63H70N4O12 · C3H7NO, reveals that out of two urea functionalized spacers, one arm is oriented above the macrocyclic cavity with strong hydrogen-bonding interactions between the urea H atoms and DMF guest, whereas, the other arm is positioned away from the macrocycle, leading to intermolecular hydrogen-bonding interactions between the urea H atoms of two adjacent pillar[5]arene macrocycles, resulting in the formation of a supramolecular dimer.

Source: Acta Crystallographica Section E - October 19, 2023 Category: Chemistry Authors: Vinodh, M. Alipour, F.H. Al-Azemi, T.F. Tags: pillararene urea substitution receptor crystal structure dimer research communications Source Type: research