Palladium/Charcoal-Catalysed Olefin Reduction for the Simple and Efficient Synthesis of Substituted gem-Diborylalkanes

Synthesis DOI: 10.1055/a-2147-1336
gem-Diborylalkanes have recently emerged as valuable synthons for diverse C–C bond-forming reactions. They represent an important class of bifunctional reagents that can be applied for the synthesis of simple to complex skeletons. Herein, we report a Pd-catalysed hydrogenation method for the synthesis of gem-diborylalkanes from the corresponding gem-diborylalkenes, which are themselves prepared from the corresponding aldehydes and ketones using known procedures. In addition, transformations of two representative gem-diborylalkane products are discussed leading to a range of functionalised derivatives. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Synthesis - September 28, 2023 Category: Chemistry Authors: Das, Kanak Kanti Ghorai, Debraj Mahato, Somenath Panda, Santanu Tags: paper Source Type: research