Chromatin accessibility, not 5mC methylation covaries with partial dosage compensation in crows

by Ana Catal án, Justin Merondun, Ulrich Knief, Jochen B. W. Wolf The evolution of genetic sex determination is often accompanied by degradation of the sex-limited chromosome. Male heterogametic systems have evolved convergent, epigenetic mechanisms restoring the resulting imbalance in gene dosage between diploid autosomes (AA) and the hemizygous sex chromosome (X). Female heterogametic systems (AAf Zf, AAm ZZm) tend to only show partial dosage compensation (0.5

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010901

Source: PLoS Genetics - September 25, 2023 Category: Genetics & Stem Cells Authors: Ana Catal án Source Type: research

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