Application of the Heck Reaction for the Synthesis of C-Glycosyl Phenolic Compounds
Synthesis DOI: 10.1055/a-2147-2788 The potential of the Heck reaction for the C-glycosylation of phenolic compounds was explored. An efficient and general methodology for the synthesis of C-glycosylated phenolic compounds based on the Heck coupling of halogenated phenolic derivatives (chromones, 2-styrylchromones, and xanthones) and sugar alkenes was developed. The protocol was applied to the preparation of previously unreported C-glycosylated 2-styrylchromones and xanthones of potential biological relevance. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Synthesis - Category: Chemistry Authors: Tom é, Sara M. Soengas, Raquel G. Silva, Artur M. S. Tags: paper Source Type: research