Prevalence of Enteric Infections in Patients on Immune Checkpoint Inhibitors and Impact on Management and Outcomes

CONCLUSIONS: GI infections in ICI-treated patients presenting with diarrhea are linked to more severe but self-limited clinical presentations and may be optimally treated with observation and supportive care alone. Routine and timely stool pathogen testing may help avert unnecessary empiric immunosuppression for suspected irEC, which has been linked to blunted antitumor responses and numerous adverse effects.PMID:37721546 | DOI:10.1093/oncolo/oyad226

Source: The Oncologist - September 18, 2023 Category: Cancer & Oncology Authors: Patrick T Magahis Deepika Satish Ngolela Esther Babady Mini Kamboj Michael A Postow Monika Laszkowska David M Faleck Source Type: research