From Histiocytoid Sweet Syndrome to Myelodysplasia Cutis

In 2005, a new histologic variant of Sweet syndrome (SS) has been described and termed histiocytoid SS (HSS). Clinically, patients had a typical SS, but on skin biopsy, the infiltrates were composed of immature nonblast myeloid cells. Nearly 50% of patients with HSS have myelodysplastic syndrome (MDS). HSS may be the first manifestation leading to the diagnosis of MDS. In 2015, a new category of myeloid dermatosis has been proposed, called myelodysplasia cutis, describing the specific skin infiltration by myelodysplastic cells in patients with MDS.

Source: Dermatologic Clinics - September 11, 2023 Category: Dermatology Authors: Marie-Dominique Vignon-Pennamen, Maxime Battistella Source Type: research