Risk evaluation of secondary malignancies after radiotherapy of breast cancer in light of the continuous development of planning techniques

Secondary cancer risk is a significant concern for women treated with breast radiation therapy due to improved long-term survival rates. We evaluated the potential of new advanced automated planning algorithms together with hybrid techniques to minimize the excess absolute risk (EAR) for secondary cancer in various organs after radiation treatment for early staged breast cancer. Using CT data set of 25 patients, we generated 4 different radiation treatment plans of different complexity, including 3-dimensional conformal radiotherapy (3D-CRT), field-in-field (FinF), hybrid-IMRT (HMRT) and automated hybrid-VMAT (HVMAT) techniques.

Source: Medical Dosimetry - August 31, 2023 Category: Radiology Authors: Savino Cilla, Francesco Deodato, Carmela Romano, Gabriella Macchia, Milly Buwenge, Mariangela Boccardi, Donato Pezzulla, Antonio Pierro, Alice Zamagni, Alessio Giuseppe Morganti Tags: Research Article Source Type: research