Estimated Absolute Percentage of Biopsied Tissue Positive for Gleason Pattern 4 (eAPP4) in Low Dose Rate Prostate Brachytherapy: Evaluation of Prognostic Utility in a Large Cohort

Prostate cancer (PCa) is the most common solid organ malignancy in Canadian males [1]. There are a variety of radiotherapy and surgical treatments available to patients; the efficacy of these treatments is often estimated based off of risk stratification systems such as those developed by the NCCN. [2]. One of the major factors in these prognostication algorithms is the Gleason grade grouping, which is calculated following histologic evaluation of prostate core biopsies. While the Gleason grade groups have been useful for prognostication and management planning, the system does have significant shortcomings [3].

Source: Radiotherapy and Oncology - August 19, 2023 Category: Radiology Authors: Geoffrey Casey, Harvey Quon, Tyler Meyer, Michael Sia, Kundan Thind, Subhadip Das, Daniel Cho, Philip McGeachy, Siraj Husain, Kevin Martell Tags: Original Article Source Type: research