A New One-Pot Synthesis of 3,6-Disubstituted Pyridazines Starting from β-Nitro-β,γ-Unsaturated Ketones

Synthesis DOI: 10.1055/a-2114-7673 A new one-pot preparation of 3,6-disubstituted pyridazines starting from β-nitro-β,γ-unsaturated ketones and hydrazine monohydrate is presented. The protocol entails two sequential steps, leading to the isolation of the title targets in satisfactory overall yields tolerating a good variety of additional functionalities. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Synthesis - July 31, 2023 Category: Chemistry Authors: Khan, Muhammad E. I. Yuan, Lixia Petrini, Marino Palmieri, Alessandro Tags: paper Source Type: research