A prime example of precisely delivered DNA

Trends Genet. 2023 Jul 20:S0168-9525(23)00158-0. doi: 10.1016/j.tig.2023.06.012. Online ahead of print.ABSTRACTIncorporating large fragments of DNA into specific genome positions is an inefficient process even when using the most cutting-edge genome-editing tools. Sun et al. recently described the prime editing-mediated recombination of opportune targets (PrimeRoot) method, which precisely and efficiently integrates large fragments of DNA into plant genomes and has enormous potential in research and agriculture.PMID:37481441 | DOI:10.1016/j.tig.2023.06.012

Source: Trends in Genetics : TIG - July 22, 2023 Category: Genetics & Stem Cells Authors: Muhammad Arslan Mahmood Julian R Greenwood Source Type: research