The Genetic Testing Reference Materials Coordination Program

The Genetic Testing Reference Materials (GeT-RM) Coordination Program was established in 2004 at the CDC, which has consistently operated collaboratively with the genetic testing community to characterize publicly available genomic DNA reference materials.1 The Program was initially centered on characterizing reference materials for mendelian genetic disorders commonly tested by clinical laboratories; however, in 2010, the GeT-RM Program reported the first collaborative effort to characterize five clinically actionable genes implicated in interindividual drug response variability: CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1.

Source: Journal of Molecular Diagnostics - July 20, 2023 Category: Pathology Authors: Stuart A. Scott Tags: Commentary Source Type: research