Medical renal mentionables: minimal change disease, membranous nephropathy and monoclonality

Advances in our understanding and ability to diagnose medical renal disease occur daily. Herein is described the recent identification of anti-nephrin antibodies in a subset of patients with minimal change disease, how the application of laser microdissection and mass spectrometry has identified multiple new antigenic targets in membranous nephropathy, and how the application of a new immunofluorescence technique targeting the junction of heavy chain and light chain constant regions may assist in determining the monoclonal nature of renal disease.

Source: Diagnostic Histopathology - March 29, 2023 Category: Pathology Authors: Meghan E. Kapp Tags: Mini-symposium: updates in genitourinary pathology Source Type: research