Combretastatins D series and analogues: from isolation, synthetic challenges and biological activities

Abstract
The combretastatin D series and its analogues, corniculatolides and isocorniculatolides belong to a class of macrocycles called cyclic diaryl ether heptanoids (DAEH). This review is intended to highlight the structure elucidation, biosynthesis, and biological activity of these compounds as well as the use of different strategies for their synthesis.

Beilstein J. Org. Chem. 2023, 19, 399–427. doi:10.3762/bjoc.19.31

Source: Beilstein Journal of Organic Chemistry - March 29, 2023 Category: Chemistry Authors: Beilstein Journal of Organic Chemistry - Syndicated Feeds Tags: combretastatin D corniculatolide isocorniculatolide macrocycles Review Source Type: research