Synthesis and reactivity of azole-based iodazinium salts

Abstract
A systematic investigation of imidazo- and pyrazoloiodazinium salts is presented. Besides a robust synthetic protocol that allowed us to synthesize these novel cyclic iodonium salts in their mono- and dicationic forms, we gained in-depth structural information through single-crystal analysis and demonstrated the ring opening of the heterocycle-bridged iodonium species. For an exclusive set of dicationic imidazoiodaziniums, we show highly delicate post-oxidation functionalizations retaining the hypervalent iodine center.

Beilstein J. Org. Chem. 2023, 19, 317–324. doi:10.3762/bjoc.19.27

Source: Beilstein Journal of Organic Chemistry - March 16, 2023 Category: Chemistry Authors: Beilstein Journal of Organic Chemistry - Syndicated Feeds Tags: building block heterocycles hypervalent compounds iodonium salts one-pot synthesis Full Research Paper Source Type: research