Drug-Induced Liver Injury due to Biologics and Immune Check Point Inhibitors

Biological agents have in the last two  decades become very important therapeutic agents, particularly for the treatment of various autoimmune disorders. The most widely used biologics are the tumor necrosis factor-α (TNF-α) receptor antagonists: infliximab, adalimumab, and etanercept. Other commonly used biological agents are interle ukin (IL)-1 receptor antagonist (Anakinra), interleukin (IL)-6 receptor antagonist (tocilizumab), and CD20 surface antigen antagonist (rituximab). The current review will however focus on TNF-α receptor antagonists.

Source: Medical Clinics of North America - February 20, 2023 Category: Primary Care Authors: Fernando Bessone, Einar S. Bj örnsson Source Type: research