LoFTK: a framework for fully automated calculation of predicted Loss-of-Function variants and genes

Loss-of-Function (LoF) variants in human genes are important due to their impact on clinical phenotypes and frequent occurrence in the genomes of healthy individuals. The association of LoF variants with compl...

Source: BioData Mining - February 2, 2023 Category: Bioinformatics Authors: Abdulrahman Alasiri, Konrad J. Karczewski, Brian Cole, Bao-Li Loza, Jason H. Moore, Sander W. van der Laan, Folkert W. Asselbergs, Brendan J. Keating and Jessica van Setten Tags: Software Source Type: research