From little subclones grow mighty oaks

Nature Reviews Clinical Oncology, Published online: 09 January 2023; doi:10.1038/s41571-022-00727-wNew genetic analyses demonstrate that the presence of low-frequency subclonal populations, including high-risk subclones, at diagnosis in multiple myeloma can contribute to disease relapse and poor clinical outcomes. Thus, sensitive detection approaches are required to detect these subclones at diagnosis together with innovative treatment strategies to eradicate low-frequency, high-risk subclones and prevent them from becoming dominant.
Source: Nature Reviews Clinical Oncology - Category: Cancer & Oncology Authors: Source Type: research